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OpenCV Image Comparison in Python: Detect Differences Like a Pro.

OpenCV image comparison

Last Updated on 22/04/2026 by Eran Feit

Introduction

This tutorial shows how to build an OpenCV image comparison pipeline in Python that detects visual differences between two images and highlights them with bounding boxes.
You will learn how to preprocess the input, isolate the two pictures inside a collage, align their sizes, compute pixel-wise differences, reduce noise, and extract clean contours of the changed regions.
The final result is a simple and effective “spot the difference” solution that is fast, easy to understand, and production-ready for many computer vision tasks.